Extinction is a natural part of life's history, yet human activity now influences the survival of many species at an unprecedented scale. The Human Constitution explores our responsibility to understand the consequences of our actions and to consider the impact of human development on the wider living world. Through Istima, extinction invites humility. It reminds us that humanity is powerful, but not separate from the systems that sustain life. The challenge is not only preventing loss where possible, but developing the wisdom, stewardship, collaboration, and long-term perspective needed to support a thriving and diverse living world for generations to come.